Which term is a specific local change in tissue, may be microscopic?

• A. Lysis
• B. Subclinical
• C. Morphologic
• D. Lesion

Answer: (D)

A lesion describes a localized abnormality in tissue. It is a specific local change in tissue structure that can be observed in the affected area and may be visible to the naked eye or only detectable under a microscope. This fits the idea of a targeted tissue alteration, which is why it’s the best choice.

Lysis refers to the destruction or breakdown of cells or tissue, not a localized abnormal area. Subclinical means the disease shows no noticeable symptoms, which is about clinical presentation rather than a local tissue change. Morphologic concerns the form or structure of tissue in general, not the occurrence of a localized alteration.