What is the source of bradykinin?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $25.99Unlock all

Study for the NATA BOC Domain 2 Clinical Evaluation and Diagnosis Test. Utilize our comprehensive flashcards and multiple-choice quiz features; each question comes with hints and thorough explanations. Prepare effectively for your certification exam!

Multiple Choice

What is the source of bradykinin?

Explanation:
Bradykinin is produced in the circulation when the enzyme kallikrein cleaves kininogen, a plasma protein that is synthesized by the liver. This makes the liver-derived plasma protein the source of bradykinin. Once formed, bradykinin acts as a potent vasodilator and increases vascular permeability, contributing to inflammation and pain. The other options describe mediators from different origins—mast cells release histamine, arachidonic acid is a precursor for prostaglandins and leukotrienes, and platelets release various factors like serotonin and thromboxane—not bradykinin.

Bradykinin is produced in the circulation when the enzyme kallikrein cleaves kininogen, a plasma protein that is synthesized by the liver. This makes the liver-derived plasma protein the source of bradykinin. Once formed, bradykinin acts as a potent vasodilator and increases vascular permeability, contributing to inflammation and pain. The other options describe mediators from different origins—mast cells release histamine, arachidonic acid is a precursor for prostaglandins and leukotrienes, and platelets release various factors like serotonin and thromboxane—not bradykinin.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy