Interruption in flow of bile through the biliary system.

• A. Exocrine
• B. Bolus
• C. Chyme
• D. Cholestasis

Answer: (D)

Cholestasis describes an interruption in the flow of bile through the biliary system. It refers to a reduced or blocked bile flow from the liver into the intestine, which can be due to intrahepatic causes (like liver disease) or extrahepatic causes (such as gallstones or bile duct obstruction). This obstruction leads to bile acid and bilirubin buildup, often producing jaundice, dark urine, and pale stools, with labs showing elevated alkaline phosphatase and conjugated bilirubin. The other terms don’t describe a blockage of bile flow: exocrine relates to glands that secrete substances via ducts, while a bolus and chyme refer to stages of digested food in the digestive tract, not to bile flow.